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Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. HGF is characterized as a . Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported . Hereditary gingival fibromatosis can occur as an isolated. Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. This report shows a case of.

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Hereditary gingival fibromatosis: Characteristics and treatment approach

Evidence of genetic heterogeneity for hereditary gingival fibromatosis. Compend Contin Educ Dent. The HGF is a rare condition of the gingival tissues characterized by enlargement of free and attached gingivae.

The connective tissue was relatively avascular with tingival inflammatory cells infiltrate. However, in some cases where it can develop as a result of rare multi-system syndromes, such as: National Center for Biotechnology InformationU.

It also was explained that in a trial on a sample of at least moderately severe Class II patients, the number of patients who needed orthognathic surgery later in life showed insignificant difference between treated children with growth modification and control group no treatment.

Hereditary gingival fibromatosis

Gingival fibromatosis can be caused by number of factors including inflammation, leukemic infiltration, and use of medications such as phenytoin, cyclosporine or nifedipine,[ 14 ] and vigabatrin. Inflamed gingival tissue due to plaque accumulation may become red.

Gingival fibromatosis, gingivectomy, hereditary gingival fibromatosis.

This report presents the clinical features and the management of 12 year old female child with a severe variety of HGF. Extraoral view showing a massive, generalized multinodular growth covering both maxillary and mandibular arch completely. After precise evaluation of risks, costs, and benefits associated with different treatment possibilities and discussing them with the patient and her parents, orthognathic surgery at appropriate time was planned.

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The tongue was pushed back. J Can Dent Assoc. Clinical examination showed persistence of the primary incisors, no eruption of the permanent incisors and lack of lip closure.

Rubor Calor Tumor Dolor Functio laesa. Am J Hum Genet. Intraoral examination showed normal development of the dentition. The gingival enlargement in HGF can be so severe that it can cover the crowns of teeth completely, causing severe functional derangement and facial disfigurement. Published online Apr 1.

No single tooth was visible due uereditary enlargement in anterior region whereas only occlusal portions of teeth were visible in posterior region. Abstract Hereditary gingival fibromatosis HGF is a rare disorder characterized by a benign, non-hemorrhagic, fibrous gingival overgrowth that can appear in isolation or hereditaary part of a syndrome.

The mandibular teeth were not at all visible except in right and left posterior region. Enlargement can be further categorized as localized fibgomatosis generalized depending on the extent of involvement [ 12 ].

Check this box if you wish to receive a copy of your message. A 12 years old female child reported to the Department of Periodontics, Government Dental College and Hospital, Nagpur complaining of gingival swelling, which caused severe compromise in her speech, mastication and aesthetics and led to considerable disfigurement of her facial profile, owing to the severity of gingival enlargement.

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Hereditary gingival fibromatosis

In the current periodontal diseases and conditions classification developed by Armitage inHGF is one of the categories of Gingival lesions of genetic origin in the Gingival Diseases section 1 – 5. Although the parents should be warned about the high risk of recurrence, the aesthetic, psychological and functional improvement justifies performing gingivectomy as soon as sufficient root development has been confirmed.

Regarding the severity of the problem and their unwillingness to attempt growth modification, the decision was made to wait until slowing down the growth after adolescent growth spurt and correcting the jaw discrepancy through bimaxillary orthognathic surgery for mandibular advancement and the impact of the posterior maxilla.

Usually the hyperplastic gingiva is pale pink to red and inflamed.

Hereditary gingival fibromatosis: Characteristics and treatment approach

A systematic review ; Hereditary gingival fibromatosis HGF is a rare condition which manifests itself by an enlarged gingival tissue covering teeth to various extents. Hereditary gingival fibromatosis in a family of Zimmerman-Laband syndrome.

HGF generally has two forms based on the extent of involved tissue, including nodular localized, mostly seen in the maxillary tuberosity and molar area fibromatodis symmetric generalized, which is more common and both arches are equally affected forms [ 13 ].

The family and postnatal history was noncontributory.