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The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months. Author information Article notes Copyright and License information Disclaimer. Bioavailability of salbutamol sulphate from different suppository formulations.

Transdermal controlled release systems. It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling emulgell.

The drug release from all the emulgels was found to follow diffusion-controlled mechanism. Medical Applications of Controlled Release. National Center for Biotechnology InformationU.


Formulation and stability of chloramphenicol gel and emulgel. Received Dec 31; Accepted May The Pharmaceutical Press; Marcel Dekker Inc; Commercially available CHL topical powder was used for comparison.

Optimization of chlorphenesin emulgel formulation

The Complete Drug Reference. Please review our privacy policy. They also exhibited higher drug release and antifungal activity than the CHL powder. The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability.

Egypt J Pharm Sci. The influence of the type of the gelling agent and the concentration of both fprmulation oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design.

Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers.

Formulation and evaluation of topical preparations containing phenol and local vesicants. A study of shear and compression deformations on hydrophilic gels of tretinoin.

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Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. Blackwell Scientific Publications; As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.


Encyclopedia of Pharmaceutical Technology. Support Center Support Center. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value.

Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: This article has been cited by other articles in PMC.

Optimization of chlorphenesin emulgel formulation

Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy.

Swarbrick J, Boylan JC, editors. The Theory and Practice of Industrial Pharmacy.

Analysis of data on the medicament release from ointments. Az J Pharm Sci. Lea and Febiger; Published online Sep 1.